I'm really late to this party, but I have a couple shirts that were printed weird and I never thought to call CS about it. They are both older, but since we're talking about sizing and positioning...
One was the long-ago original run of After All This Time [Always], which was (A) my first Anvil shirt (ew), and (B) a known issue that they were printed in a strange off-center way.
The other was the Hogwarts Waitlist one. I bought it in Men's XL and the words are really REALLY high up on the chest, only 1 inch from the collar. This may have been intended, but again since we're talking positioning, the text is not very large vertically and IMHO should have been positioned down more on the chest instead of on the collarbone. Most other shirts I buy from woot or other places start at least 2" down from the collar for large designs, or maybe 3" down from the collar for (vertically) smaller designs.
The second picture gives you an idea how silly the positioning looks.